Lihlahisoa

Lihlahisoa tsa PO li na le litlamorao tse ntle tse khahlanong le dandruff le tse thibelang ho hlohlona, ​​mochini o ikhethileng oa anti-dandruff, solubility e ntle haholo le ho kopanya hape, polokeho, e se nang chefo, e sa thabiseng, 'me e sebelisoa haholo ho shampoo le lihlahisoa tsa tlhokomelo ea moriri.PO e na le litlamorao tse ntle tsa antipruritic, hape e na le ts'ebetso ea ho koala le ho ntša monko, ka hona e sebelisitsoe litlolo tsa ho hlapa ho fihlela litholoana tse ntle.PO e na le phello e pharaletseng ea ho bolaea li-fungus le hlobo, 'me e na le phello e ntle ea phekolo maotong le libokong tsa letsoho.E ka sebelisoa e le se sireletsang litlolong, e le bactericide ka sesepa, le e le ntho e matlafatsang.Ka hona, PO ke anti-dandruff le antipruritic bactericide e sebetsang ka bongata, e sebelisoang haholo lihlahisoa tsa shampoo le tsa moriri, litlolo tsa ho hlapa, litlolo le litlolo.

Piroctone olamine, letsoai la ethanolamine la hydroxamic acid derivative Piroctone, ke hydroxypyridone anti-mycotic agent.Piroctone olamine e kenella ka har'a lera la sele 'me e etsa metsoako e nang le li-ion tsa tšepe, e thibelang metabolism ea matla ho mitochondria[1].Piroctone olamine (PO) ke letsoai la ethanolamine la Piroctone e tsoang ho hydroxamic acid.Mefuta eohle ea Candida e bonts'a maemo a tlase a inhibitory concentrations (MICs) bakeng sa Piroctone olamine (0.125-0.5 μg/mL) le Amphotericin B (AMB) (0.03-1 μg/mL).

Mosebetsi ona o ne o reretsoe ho hlahloba mosebetsi oa antifungal oa Piroctone olamine ho phekola candidiasis ea ka mpeng ka mokhoa oa liteko o sebelisang litoeba tsa Switzerland.Kalafo ka Piroctone olamine (0.5 mg / kg) e etsoa lihora tse 72 ka mor'a tšoaetso ka tsamaiso ea intraperitoneal.Ho bapisa, sehlopha sa liphoofolo (n=6) se phekoloa ka Amphotericin B (0.5 mg/kg).Tlhahlobo ea mycological e etsoa ka ho bokella sebete, spleen le liphio.Lintlha tse mabapi le kholo ea fungal le lefu li hlahlojoa ka lipalo-palo ke tlhahlobo ea Seithuti le tlhahlobo ea phapang, ka boemo ba bohlokoa bo behiloeng ho P.<0.05.Phapano ea lintlha tsa kholo ea fungal lipakeng tsa sehlopha sa taolo le lihlopha tsa kalafo (Piroctone olamine le Amphotericin B) e bohlokoa ka lipalo (P).<0.05)